Conceptual agreement that a patch on the issue would be accepted (if of sufficient quality)

Activity management components

Case management components (CiviCase)

Contribution management components (CiviContribute)

Event management components (CiviEvent)

Composing, sending, and tracking email blasts

Membership management components (CiviMember)

Built-in reporting components (CiviReport)

Subsystem for identifying and merging duplicate contacts

Built-in data-export system

Built-in data-import system

Authentication API

Payment processing

Built-in contact search components (Advanced Search, Search Builder, etc)